Silver Moon is in her teens when her Cheyenne village is destroyed by Colonel John Chivington's cavalry unit. As Silver Moon grows, she becomes consumed with hatred until her one goal is to kill the man responsible. But when a smallpox epidemic breaks out among the Cheyenne, Christian nurse Breanna Baylor Brockman comes to care for the sick, and the nurse's compassion for Silver Moon and her people begins the girl's journey toward conversion and healing.