The Holy Spirit helps readers grow in awareness of the Holy Spirit's presence and movement in their lives. Each author is a faculty member of Boston College's School of Theology and Ministry and offers a reflection on the Holy Spirit in light of their own particular expertise and grounded in the discipline and/or field of their study (Scripture; systematic theology; pastoral ministry; ethics; spirituality, among others).

The book is organized in three parts: the first attends to how we become of aware of the Holy Spirit's active and constant presence in our lives; the second considers how the tradition has identified the Holy Spirit's movement among us; and the third explores various ways in which we have responded to the Holy Spirit.