OF all human pursuits, the pursuit of wisdom is the more perfect, the more sublime, the more useful, and the more agreeable. The more perfect, because in so far as a man gives himself up to the pursuit of wisdom, to that extent he enjoys already some portion of true happiness. Blessed is the man that shall dwell in wisdom (Ecclus xiv, 22). The more sublime, because thereby man comes closest to the likeness of God, who hath made all things in wisdom (Ps. ciii, 24). The more useful, because by this same wisdom we arrive at the realm of immortality. The desire of wisdom shall lead to an everlasting kingdom (Wisd. vi, 21). The more agreeable, because her conversation hath no bitterness, nor her company any weariness, but gladness and joy (Wisd. viii, 16). But on two accounts it is difficult to proceed against each particular error: first, because the sacrilegious utterances of our various erring opponents are not so well known to us as to enable us to find reasons, drawn from their own words, for the confutation of their errors: for such was the method of the ancient doctors in confuting the errors of the Gentiles, whose tenets they were readily able to know, having either been Gentiles themselves, or at least having lived among Gentiles and been instructed in their doctrines. Secondly, because some of them, as Mohammedans and Pagans, do not agree with us in recognizing the authority of any scripture, available for their conviction, as we can argue against the Jews from the Old Testament, and against heretics from the New. But these receive neither: hence it is necessary to have recourse to natural reason, which all are obliged to assent to. But in the things of God natural reason is often at a loss.