Is there a higher creative intelligence, is there a God? Is there a spirit, a spiritual dimension? Does our life end with death? Do humans have a free will? What is our "ego"? Are life and spirit mere incidental products of matter? Was everything really created by the Big Ban? These and many other questions occupy all our minds at some time or other Natural science and religions offer diverse and often mutually excluding and contradictory answers. Natural science preaches materialisms. Neither God nor a discarnate spirit, not even our "ego" or our free will find acceptance in the tenets of natural science and modern brain research. Is this materialism, so characteristic of our times, the right notion? The author is a practicing medical specialist and a professor at a German University of Applied Sciences. he has lectured at a natural scientific-technical faculty for many years. He is convinced that materialism is not the right explanation and the believes that he can prove this by means of confirmed natural scientific knowledge. With his consistent observation beyond the horizons of all important scientific fields and with impressive logic he leads us towards his own perception of the real world. Natural science and religions are smoothly interconnected here by means of philosophy. In the end even death loses its horror. In so doing this book may also provide assistance and consolation for those afraid of their own death or being directly confronted with the death of a beloved one.