Our lives re full of non-material experiences and emotions as love, happiness, joy, wonder, empathy, deep connection between mother and child, sense of morality, achievement, realization; all of which speak of our spiritual nature. There is however a great divide nowadays between the purely scientific and materialistic view of the world which denies the existence of anything spiritual or non-material; and the view that we are much more than pure quarks and electrons and we are endowed with a rich Spiritual, purposeful and meaningful life. The book tackles profound questions regarding our existence. Explain the facts supporting evolution as well as to the fact that evolution does not exclude the presence of the Creator who started the process. Also approaches the main subject of consciousness and the many Neurological and physiological explanations for it and then the fact that although we understand how the brain works to some degree that is not enough to explain consciousness which again points toward transcendence beyond the physical body; then it settles the big controversy of Free Will from Neurophysiological standpoint and then reviews the big gap and differences between Religion and Spirituality and the positive and also negative aspects of religion which have moved the current generation apart from those institutions. The book concludes reporting the fact that for both Science and Spirituality the ultimate and deep answers of our existence and the origin of life and the universe lie on Faith since most of those questions are not falsifiable.