Luther's Works: The American Edition, published by Concordia and Fortress Press between 1955 and 1986, comprises fifty-five volumes. These are a selection representing only about a third of Luther's works in the Latin and German of the standard Weimar Edition, not including the German Bible.

The Reformer's lectures on the First Book of Moses must be numbered among the great works in the field of exegetical writing. Unlike many scholars who have undertaken to expound Genesis, Luther is not afraid to adhere strictly to the letter of what Moses wrote. He does not indulge in wild allegories. He does not tear words or sentences out of their context. He knows that Genesis is the Word of God. Therefore he approaches the book with awe and reverence. His is a genuinely Christian commentary.

This volume discusses Genesis 1-5, including the Creation, the Fall, the First Brothers, and the line of Adam.