A woman has been arrested in the streets of Rome. She's young. She's beautiful. She's covered in blood. And she claims to be an ancient prophet in search of a mystical amulet hidden somewhere within the city.

Ex-priest Tom Shaman teams up with a headstrong policewoman to unravel the mystery. But within Rome's churches and corridors of power, stealthy enemies are conspiring against them. And soon the woman's deadly visions begin to come true . . .