This volume, the third in the series MediTo, investigates the changing landscapes of Tuscany during Late Antiquity and the Early Middle Ages. Through a selection of thematic case studies, presented initially during the second International workshop held in Paganico (Grosseto, Italy) in June 2019 and here further developed, the volume explores the concepts of settlement, economic, and societal changes in both Tuscany and its broader Mediterranean context over the course of several centuries. Together, the contributions gathered here showcase how cities and rural settlements, when studied in their archaeological and historical context, shed light on a dynamic landscape in which natural resources played a crucial role in defining the success or later abandonment of sites.