This study is a comparative study of the asham sacrificial concepts of the Israelites (Jews) of the Old Testament times and the contemporary Asante religion of the Asante people of Ghana in West Africa. The results from the study show that there are similar ideas that the Israelite and the Asante religions have on guilt sacrifice. However, the reality must not be overlooked that there are significant differences in the practice of each of the religions. Even though the Israelites and Asante are similar in some of their religious concepts, they are dissimilar in reality and practice.