The contributors to this volume illustrate the way in which exegesis of the book of Isaiah was developed in early Christianity. Reception unfolded within spaces opened, shaped, and defined along Judaeo-Christian borderlines. The book of Isaiah was of utmost importance to the first Jesus followers and their literary production, particularly in the way they articulated their beliefs. Consequently, scholars have often referred to Isaiah as "the fifth Gospel." The present volume collects investigations into the specific ways the book of Isaiah was received in various early Christian contexts - from the canonical gospels to early Syriac Christian literature. The contributors explore the different modes and purposes of reading Isaiah and integrating its ideas, style, and concepts into new writings.